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Malignant cells displayed moderate to strong nuclear positivity.
GENE INFORMATION
Gene name
EXOSC3 (HGNC Symbol)
Synonyms
CGI-102, hRrp-40, hRrp40p, p10, RRP40, Rrp40p
Description
Exosome component 3 (HGNC Symbol)
Entrez gene summary
This gene encodes a non-catalytic component of the human exosome, a complex with 3'-5' exoribonuclease activity that plays a role in numerous RNA processing and degradation activities. Related pseudogenes of this gene are found on chromosome 19 and 21. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2012]