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Malignant cells exhibited weak to moderate cytoplasmic immunoreactivity. Several cases of liver cancers as well as a few cases of colorectal, ovarian and pancreatic cancers showed strong staining. A majority of malignant lymphomas and skin cancers were negative.
GENE INFORMATION
Gene name
SOBP (HGNC Symbol)
Synonyms
FLJ10159
Description
Sine oculis binding protein homolog (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene is a nuclear zinc finger protein that is involved in development of the cochlea. Defects in this gene have also been linked to intellectual disability. [provided by RefSeq, Mar 2011]