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Carcinoids and several colorectal cancers along with a few renal, gastric, urothelial and ovarian cancers showed weak to moderate cytoplasmic staining with occasional membranous or nuclear immunoreactivity. A rare case of pancreatic cancer was strongly stained. Remaining cancer tissues were weakly stained or generally negative.
GENE INFORMATION
Gene name
HECA (HGNC Symbol)
Synonyms
dJ225E12.1, HDC, HDCL, hHDC
Description
Hdc homolog, cell cycle regulator (HGNC Symbol)
Entrez gene summary
This gene encodes the homolog of the Drosophila headcase protein, a highly basic, cytoplasmic protein that regulates the re-entry of imaginal cells into the mitotic cycle during adult morphogenesis. In Drosophila, the encoded protein also inhibits terminal branching of neighboring cells during tracheal development. [provided by RefSeq, Jul 2008]