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Most cancers displayed moderate cytoplasmic positivity. Cases of colorectal, breast and testis cancers showed strong staining. Several melanomas, lung, urothelial, renal and gastric cancers were weakly stained or negative.
GENE INFORMATION
Gene name
PODXL2 (HGNC Symbol)
Synonyms
endoglycan, PODLX2
Description
Podocalyxin-like 2 (HGNC Symbol)
Entrez gene summary
This gene is a member of the CD34 family of cell surface transmembrane proteins, which are characterized by an N-terminal extracellular mucin domain, globular and stalk domains, a single pass transmembrane region, and a charged cytoplasmic tail. The encoded protein is a ligand for vascular selectins. [provided by RefSeq, Oct 2012]