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Most cancers were weakly stained in cytoplasm or were negative. Several cases of colorectal, prostate and liver cancers were moderately stained.
GENE INFORMATION
Gene name
TTLL5 (HGNC Symbol)
Synonyms
KIAA0998
Description
Tubulin tyrosine ligase-like family member 5 (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the tubulin tyrosine ligase like protein family. This protein interacts with two glucocorticoid receptor coactivators, transcriptional intermediary factor 2 and steroid receptor coactivator 1. This protein may function as a coregulator of glucocorticoid receptor mediated gene induction and repression. This protein may also function as an alpha tubulin polyglutamylase.[provided by RefSeq, Feb 2010]