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Ubiquitous cytoplasmic expression, most abundant in glandular cells.
ANTIBODY IHC RELIABILITY
Data reliability description
Antibody staining mainly consistent with RNA expression data. Pending external verification. Secreted protein, tissue location of RNA and protein might differ and correlation is complex.
Several papillary adenocarcinomas of thyroid and colorectal cancer as well as a few endometrial cancers showed moderate cytoplasmic immunoreactivity in a granular pattern. Remaining cancer tissues were weakly stained or negative.
Most cancer tissues showed moderate to strong cytoplasmic staining, seen with a granular pattern. Lymphomas along with head and neck cancers were negative.