We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
Few squamous cell carcinomas and urothelial cancers showed weak cytoplasmic and/or nuclear staining. A single case of duct carcinoma of breast was moderately positive. Remaining cancer tissues were negative.
GENE INFORMATION
Gene name
ULBP3 (HGNC Symbol)
Synonyms
RAET1N
Description
UL16 binding protein 3 (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene is one of several related ligands of the KLRK1/NKG2D receptor, which is found in primary NK cells. Binding of these ligands to the receptor activates several signal transduction pathways, including the JAK2, STAT5, and ERK pathways. The encoded protein is expressed solubly and on the surface of many tumor cells, making it potentially an important target for therapeutics. [provided by RefSeq, Nov 2015]