We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
A majority of the malignant cells displayed weak cytoplasmic staining or were negative. Several cases of testicular seminomas, urothelial and pancreatic cancers displayed moderate cytoplasmic and nuclear staining.
GENE INFORMATION
Gene name
GIMAP6 (HGNC Symbol)
Synonyms
FLJ22690, IAN6
Description
GTPase, IMAP family member 6 (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the GTPases of immunity-associated proteins (GIMAP) family. GIMAP proteins contain GTP-binding and coiled-coil motifs, and may play roles in the regulation of cell survival. Decreased expression of this gene may play a role in non-small cell lung cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is found in a cluster with seven additional GIMAP genes on the long arm of chromosome 7. [provided by RefSeq, Sep 2011]
B4DH95 [Direct mapping] GTPase IMAP family member 6; cDNA FLJ50958, highly similar to Homo sapiens GTPase, IMAP family member 6 (GIMAP6), transcript variant 1, mRNA
Show all
Phobius predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)