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Most cancers showed weak cytoplasmic and membranous positivity or were negative. Carcinoids and several endometrial and urothelial cancers were moderately stained.
Cancer cells showed moderate to strong cytoplasmic and membranous positivity with a granular pattern.
GENE INFORMATION
Gene name
FLOT1
Synonyms
Description
Flotillin 1 (HGNC Symbol)
Entrez gene summary
Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal transduction. FLOT1 encodes a caveolae-associated, integral membrane protein. The function of flotillin 1 has not been determined. [provided by RefSeq, Jul 2008]