We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
Fields »
 

Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

Cancer

Prognosis

Category

Score

Score

Score

Antibodies

Column

 
 
ABOUT
HELP
BLOG
  • THE HUMAN PROTEOME
  • THE HUMAN TISSUES
  • THE HUMAN CELL
  • HUMAN PATHOLOGY
  • PROTEIN CLASSES
  • PROTEIN EVIDENCE
    • NEWS
    • BLOG
    • EVENTS
    • PRESS ROOM
    • LEARN
    • DICTIONARY
    • METHODS
    • CELL LINES
  • THE PROJECT
  • INTRODUCTION
  • ORGANIZATION
  • PUBLICATIONS
  • PUBLICATION DATA
  • ANTIBODY SUBMISSION
  • ANTIBODY AVAILABILITY
  • LINKS
  • CONTACT
  • TECHNICAL DATA
  • ANTIBODY VALIDATION
  • ASSAYS & ANNOTATION
  • DISCLAIMER
  • DOWNLOADABLE DATA
  • HELP & FAQ
  • LICENCE & CITATION
  • PRIVACY STATEMENT
  • RELEASE HISTORY
ANO7
  • TISSUE

  • CELL

  • PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

ANO7

Gene description

Anoctamin 7

Protein class

Predicted membrane proteins
Predicted secreted proteins

Predicted localization

Membrane,Secreted

Number of transcripts

4
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Tissue enhanced (prostate, stomach)
GTEx:Tissue enhanced (prostate)
FANTOM5:Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in prostate and stomach glands.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly consistent with RNA expression data. Presumed off target binding observed and disregarded. Pending external verification.

Reliability score

Uncertain based on 1 antibody.
HPA035730
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Prostate

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (prostate, stomach)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (prostate)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

ANO7 (HGNC Symbol)

Synonyms

IPCA-5, NGEP, PCANAP5, PCANAP5L, TMEM16G

Description

Anoctamin 7 (HGNC Symbol)

Entrez gene summary

This prostate-specific gene encodes a cytoplasmic protein, as well as a polytopic membrane protein which may serve as a target in prostate cancer diagnosis and immunotherapy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2011]

Chromosome

2

Cytoband

q37.3

Chromosome location (bp)

241188509 - 241225377

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000146205 (version 83.38)

Entrez gene

50636

UniProt

Q6IWH7 (UniProt - Evidence at protein level)

neXtProt

NX_Q6IWH7

Antibodypedia

ANO7 antibodies

PROTEIN BROWSER

ANO7-001
ANO7-002
ANO7-008
ANO7-010

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ANO7-001
ENSP00000274979
ENST00000274979
Q6IWH7 [Direct mapping]
Anoctamin-7
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   9TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005229 [intracellular calcium activated chloride channel activity]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005783 [endoplasmic reticulum]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0006821 [chloride transport]
GO:0006869 [lipid transport]
GO:0016021 [integral component of membrane]
GO:0017128 [phospholipid scramblase activity]
GO:0030054 [cell junction]
GO:0034220 [ion transmembrane transport]
GO:0055085 [transmembrane transport]
GO:0061589 [calcium activated phosphatidylserine scrambling]
GO:0061590 [calcium activated phosphatidylcholine scrambling]
GO:0061591 [calcium activated galactosylceramide scrambling]
GO:1902476 [chloride transmembrane transport]
Show all
933 aa
105.5 kDa
Yes 9
ANO7-002
ENSP00000383985
ENST00000402530
Q6IWH7 [Direct mapping]
Anoctamin-7
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005229 [intracellular calcium activated chloride channel activity]
GO:0005622 [intracellular]
GO:0005783 [endoplasmic reticulum]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0006821 [chloride transport]
GO:0006869 [lipid transport]
GO:0016021 [integral component of membrane]
GO:0030054 [cell junction]
GO:0034220 [ion transmembrane transport]
GO:0055085 [transmembrane transport]
Show all
179 aa
19.6 kDa
Yes 0
ANO7-008
ENSP00000403625
ENST00000451047
H7C220 [Direct mapping]
Anoctamin
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   3TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0016021 [integral component of membrane]
GO:0061588 [calcium activated phospholipid scrambling]
Show all
186 aa
20.9 kDa
No 3
ANO7-010
ENSP00000385418
ENST00000402430
Q6IWH7 [Direct mapping]
Anoctamin-7
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   9TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005229 [intracellular calcium activated chloride channel activity]
GO:0005622 [intracellular]
GO:0005783 [endoplasmic reticulum]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0006821 [chloride transport]
GO:0006869 [lipid transport]
GO:0016021 [integral component of membrane]
GO:0030054 [cell junction]
GO:0034220 [ion transmembrane transport]
GO:0055085 [transmembrane transport]
Show all
883 aa
99.8 kDa
Yes 9

Contact

  • BLOG
  • PRESS ROOM
  • contact@proteinatlas.org

The Project

  • INTRODUCTION
  • ORGANIZATION
  • PUBLICATIONS
  • DOWNLOADABLE DATA

The Human Protein Atlas

  • ANTIBODY AVAILABILITY
  • LICENCE & CITATION
  • HELP & FAQ
The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.