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Cancer tissues showed weak to moderate nuclear/nucleolar and occasional cytoplasmic and membranous staining. A few cases of melanomas, basal cell carcinomas, urothelial and pancreatic cancers showed strong positivity.
GENE INFORMATION
Gene name
C10orf11 (HGNC Symbol)
Synonyms
CDA017, OCA7
Description
Chromosome 10 open reading frame 11 (HGNC Symbol)
Entrez gene summary
This gene encodes a leucine-rich repeat protein. The encoded protein is thought to play a role in melanocyte differentiation. Mutations in this gene have been associated with autosomal recessive oculocutaneous albinism 7 (OCA7). Alternatively spliced transcript variants have been identified. [provided by RefSeq, Mar 2015]