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Tumour tissues showed moderate to strong nuclear positivity with additional cytoplasmic immunoreactivity in several cases.
GENE INFORMATION
Gene name
BUB3 (HGNC Symbol)
Synonyms
BUB3L
Description
BUB3 mitotic checkpoint protein (HGNC Symbol)
Entrez gene summary
This gene encodes a protein involved in spindle checkpoint function. The encoded protein contains four WD repeat domains and has sequence similarity with the yeast BUB3 protein. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]