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Cytoplasmic staining of varying intensities was displayed in immune cells in tumor stroma in most cancers. Additional weak to moderate cytoplasmic positivity was observed in a small subset of tumor cells in a few cases of several cancers.
GENE INFORMATION
Gene name
SLAMF8 (HGNC Symbol)
Synonyms
BLAME, CD353, SBBI42
Description
SLAM family member 8 (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the CD2 family of cell surface proteins involved in lymphocyte activation. These proteins are characterized by Ig domains. This protein is expressed in lymphoid tissues, and studies of a similar protein in mouse suggest that it may function during B cell lineage commitment. The gene is found in a region of chromosome 1 containing many CD2 genes. [provided by RefSeq, Jul 2008]