We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
Head and neck cancers and thyroid cancers along with a few cases of melanomas, colorectal, skin, testicular and urothelial cancers exhibited weak to moderate nuclear and cytoplasmic positivity. Remaining cancer tissues were negative.
Several cases of breast, ovarian, cervical, skin, pancreatic and urothelial cancers displayed moderate to strong cytoplasmic and membranous positivity. Most cases of lung, stomach along with rare colorectal, prostate, endometrial, liver, head and neck cancers showed moderate positivity. Remaining cancers were weakly stained or negative.
GENE INFORMATION
Gene name
TAF1D (HGNC Symbol)
Synonyms
JOSD3, MGC5306, TAF(I)41
Description
TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa (HGNC Symbol)
Entrez gene summary
TAF1D is a member of the SL1 complex, which includes TBP (MIM 600075) and TAF1A (MIM 604903), TAF1B (MIM 604904), and TAF1C (MIM 604905), and plays a role in RNA polymerase I transcription (Wang et al., 2004 [PubMed 15520167]; Gorski et al., 2007 [PubMed 17318177]).[supplied by OMIM, Jun 2009]