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The majority of endometrial cancers showed moderate to strong cytoplasmic positivity. Most cases of prostate and testicular cancers showed cases of weak to moderate cytoplasmic immunoreactivity. Several liver cancers were weakly stained. Remaining malignant cells were mainly negative.
GENE INFORMATION
Gene name
TACR3 (HGNC Symbol)
Synonyms
NK3R
Description
Tachykinin receptor 3 (HGNC Symbol)
Entrez gene summary
This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin neurokinin 3, also referred to as neurokinin B. [provided by RefSeq, Jul 2008]