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Most cancer tissues displayed weak to moderate cytoplasmic and membranous immunoreactivity. Melanoma, colorectal, ovarian, gastric and pancreatic cancers were strongly stained.
GENE INFORMATION
Gene name
PCDH7 (HGNC Symbol)
Synonyms
BH-Pcdh, PPP1R120
Description
Protocadherin 7 (HGNC Symbol)
Entrez gene summary
This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes a protein with an extracellular domain containing 7 cadherin repeats. The gene product is an integral membrane protein that is thought to function in cell-cell recognition and adhesion. Alternative splicing yields isoforms with unique cytoplasmic tails. [provided by RefSeq, Jul 2008]