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Malignant carcinoids and hepatocellular carcinomas showed moderate to strong cytoplasmic staining. Several renal cancers were moderately stained. Remaining malignant cells were weakly stained or negative.
GENE INFORMATION
Gene name
MUC3A (HGNC Symbol)
Synonyms
MUC3
Description
Mucin 3A, cell surface associated (HGNC Symbol)
Entrez gene summary
The mucin genes encode epithelial glycoproteins, some of which are secreted and some membrane bound. Each of the genes contains at least one large domain of tandemly repeated sequence that encodes the peptide sequence rich in serine and/or threonine residues, which carries most of the O-linked glycosylation (Gendler and Spicer, 1995 [PubMed 7778880]).[supplied by OMIM, Aug 2008]