Expression of OR1S1 in cancer - Summary - The Human Protein Atlas

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OR1S1

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	OR1S1
Gene description	Olfactory receptor, family 1, subfamily S, member 1 (gene/pseudogene)
Protein class	G-protein coupled receptors Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Not detected
HPA (normal tissue):	Not detected

Protein evidence

No evidence

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Caution, targets protein from more than one gene.
Reliability score	Uncertain based on 1 antibody. HPA049304
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA049304

GENE INFORMATION
Gene name	OR1S1 (HGNC Symbol)
Synonyms	OST034
Description	Olfactory receptor, family 1, subfamily S, member 1 (gene/pseudogene) (HGNC Symbol)
Entrez gene summary
Chromosome	11
Cytoband	q12.1
Chromosome location (bp)	58214745 - 58215722
Protein evidence	No evidence (all genes)
Ensembl	ENSG00000172774 (version 83.38)
Entrez gene
UniProt	Q8NH92 (UniProt - Inferred from homology)
neXtProt	NX_Q8NH92
Antibodypedia	OR1S1 antibodies

PROTEIN BROWSER

OR1S1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
OR1S1-201 ENSP00000311688 ENST00000309433	Q8NH92 [Direct mapping] Olfactory receptor 1S1 Show all	G-protein coupled receptors Odorant/olfactory and gustatory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 8TM proteins predicted by MDM Show all	GO:0004888 [transmembrane signaling receptor activity] GO:0004930 [G-protein coupled receptor activity] GO:0004984 [olfactory receptor activity] GO:0005886 [plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0016021 [integral component of membrane] GO:0050907 [detection of chemical stimulus involved in sensory perception] GO:0050911 [detection of chemical stimulus involved in sensory perception of smell] Show all	325 aa 36.7 kDa	No	8

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.