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Most cancer cells exhibited weak to moderate cytoplasmic immunoreactivity combined with nuclear staining in several cases. Most lymphomas and several cases of lung, renal and liver cancer were negative.
GENE INFORMATION
Gene name
SCAI (HGNC Symbol)
Synonyms
C9orf126, FLJ36664, NET40
Description
Suppressor of cancer cell invasion (HGNC Symbol)
Entrez gene summary
This gene encodes a regulator of cell migration. The encoded protein appears to function in the RhoA (ras homolog gene family, member A)-Dia1 (diaphanous homolog 1) signal transduction pathway. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2010]