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Moderate to strong cytoplasmic and nuclear positivity was observed in cancer tissues. Additional membranous staining was seen in breast, colorectal, ovarian and renal cancers.
Most cancer cells showed moderate cytoplasmic positivity with additional nucleolar staining in several cases. A few non-Hodgkins lymphomas and melanomas were strongly stained. Most gliomas were weakly stained.
GENE INFORMATION
Gene name
FAM53B (HGNC Symbol)
Synonyms
bA12J10.2, KIAA0140, smp
Description
Family with sequence similarity 53, member B (HGNC Symbol)