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Most malignant cells showed weak to moderate cytoplasmic and membranous immunoreactivity. Colorectal cancer showed strong luminal membranous staining. Several cases of malignant melanoma, urothelial and ovarian cancers were strongly stained.
Most cancers showed weak to moderate cytoplasmic positivity. Rare cases of endometrial, testis, urothelial, pancreatic and liver cancers showed strong positivity. Several renal cells carcinomas, hepatocellular carcinomas and stomach cancers were weakly stained or negative.
GENE INFORMATION
Gene name
STRN3 (HGNC Symbol)
Synonyms
SG2NA
Description
Striatin, calmodulin binding protein 3 (HGNC Symbol)