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ABCB8
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TISSUE ATLAS PRIMARY DATA LIVER

GENE/PROTEIN

Antibody validation


Dictionary

Liver

Tissue proteome

Liver

LIVER - Expression summary

Protein expressioni

The protein expression bar, with the units not detected (n), low (l), medium (m) and high (h), is based on a best estimate of the true protein expression for proteins where the antibody staining pattern has been analyzed by knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. For details, see Assays & annotation.

h
m
l
n

RNA expressioni

RNA expression shows average values based on RNA-seq data generated by HPA, the Genotype-Tissue Expression (GTEx) consortium or the FANTOM5 consortium.

Read more

HPA:4.7TPM
GTEx:5.8RPKM
FANTOM5:39.7Tags Per Million

LIVER - Annotated protein expressioni

The detailed normal tissue page shows images of the stained tissue, together with antibody staining and expression level of the cell types. A knowledge-based annotated protein expression is provided for each cell type at the top of the page and the staining level of the individual antibodies is given underneath each antibody ID.

Samples from up to three different individuals have been stained for each antibody. The gender, age and tissue characterization are reported for each individual (patient) and are viewable when clicking on the image for magnification.

The images can be clicked for an enlarged view that can be panned. From the enlarged view, all stained images for all antibodies can be browsed (represented by miniature images). The miniature image with an orange overlay is the currently displayed image.

For histological reference, view the histological dictionary.

Annotated protein
expression

Bile duct cells:Medium
Hepatocytes:Not detected
 

Antibody stainingi

This score describes the level of antibody staining observed in the annotated cell types as not detected, low, medium, or high. It is based on the staining intensity and fraction of stained cells.

Read more

Antibody HPA045187

 

Bile duct cells

Medium  

Hepatocytes

Not detected  
 
 
 

LIVER - HPA RNA-seqi

The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.

Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. TPM (transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.

Read more

Average TPM

4.7

N/A Female, age 60 Sample 1
TPM: 7.8
overview Male, age 54 Sample 2
TPM: 3.9
Cell types%
Hepatocytes: 80
Fibroblasts: 15
Other cell types: 5
overview Male, age 74 Sample 3
TPM: 5.3
Cell types%
Hepatocytes: 85
Fibroblasts: 5
Other cell types: 10
overview Female, age 62 Sample 4
TPM: 1.2
Cell types%
Hepatocytes: 70
Fibroblasts: 10
Other cell types: 20
overview Male, age 78 Sample 5
TPM: 1.6
Cell types%
Hepatocytes: 75
Fibroblasts: 5
Other cell types: 20
overview Male, age 53 Sample 6
TPM: 4.8
Cell types%
Hepatocytes: 80
Fibroblasts: 5
Other cell types: 15
overview Male, age 77 Sample 7
TPM: 2.4
Cell types%
Hepatocytes: 75
Fibroblasts: 5
Other cell types: 20
overview Female, age 72 Sample 8
TPM: 9.5
Cell types%
Hepatocytes: 50
Fibroblasts: 10
Other cell types: 40
overview Male, age 70 Sample 9
TPM: 2.6
Cell types%
Hepatocytes: 65
Fibroblasts: 10
Other cell types: 25
overview Female, age 23 Sample 10
TPM: 8.1
Cell types%
Hepatocytes: 70
Fibroblasts: 5
Other cell types: 25

LIVER - GTEx RNA-seqi

RNA-Seq data is reported as average RPKM (reads per kilobase per million mapped reads), generated by the Genotype-Tissue Expression (GTEx) project. More information can be found on the GTEx portal.

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. RPKM values of the individual samples are presented next to the box plot.

Read more

Average RPKM

5.8

GTEx sample id

Sample description

RPKM

Liver
RPKM: 5.8
Samples: 119

Max RPKM: 10.4
Min RPKM: 2.6
Std RPKM: 1.3
Median RPKM: 5.5
GTEX-13N11-0926-SM-5IJG2 50-59 years, female 10.4
GTEX-QEL4-1226-SM-447A4 50-59 years, male 9.6
GTEX-S32W-1926-SM-4AD63 50-59 years, female 9.5
GTEX-139TU-0826-SM-5IJFG 60-69 years, male 8.4
GTEX-1497J-0726-SM-5Q5D1 60-69 years, male 8.2
GTEX-REY6-1226-SM-48FDR 60-69 years, male 8.2
GTEX-X4XY-1626-SM-46MVN 60-69 years, male 8.2
GTEX-S4Z8-0526-SM-4AD4T 60-69 years, male 8.1
GTEX-13SLX-1226-SM-5S2Q6 50-59 years, female 8.0
GTEX-ZVT3-1626-SM-5GU66 60-69 years, female 7.9
GTEX-147F4-1426-SM-5LUA8 50-59 years, male 7.8
GTEX-XBEC-1526-SM-4AT68 50-59 years, male 7.8
GTEX-146FH-1526-SM-5NQBU 50-59 years, female 7.7
GTEX-S33H-1626-SM-4AD68 30-39 years, male 7.7
GTEX-WQUQ-1926-SM-4OOSA 60-69 years, male 7.7
GTEX-YFC4-1526-SM-5IFJS 40-49 years, female 7.4
GTEX-132NY-0926-SM-5P9G3 60-69 years, male 7.3
GTEX-13QJC-0726-SM-5RQJK 60-69 years, female 7.3
GTEX-14A5I-1726-SM-5QGQ5 50-59 years, female 7.3
GTEX-13N2G-0926-SM-5IFGJ 60-69 years, male 7.1
GTEX-QDVN-0826-SM-48TZ2 50-59 years, male 7.1
GTEX-139TS-1426-SM-5IFJD 60-69 years, male 7.0
GTEX-P78B-1326-SM-3P611 40-49 years, female 7.0
GTEX-R53T-0326-SM-48FEC 50-59 years, female 7.0
GTEX-X261-1726-SM-4PQYT 50-59 years, male 7.0
GTEX-12WSG-0626-SM-5FQTQ 50-59 years, female 6.9
GTEX-OOBJ-0826-SM-3NB2K 60-69 years, male 6.9
GTEX-UPIC-0926-SM-4IHLV 20-29 years, female 6.9
GTEX-13NZ9-1326-SM-5MR3V 50-59 years, male 6.8
GTEX-13113-1326-SM-5GCOI 60-69 years, female 6.7
GTEX-13NYB-1026-SM-5IFH3 40-49 years, male 6.6
GTEX-145MF-0826-SM-5QGQA 50-59 years, male 6.6
GTEX-Y5V5-0926-SM-4VBPZ 60-69 years, female 6.6
GTEX-1269C-0626-SM-5FQSS 60-69 years, female 6.4
GTEX-X4EO-1126-SM-4QARQ 60-69 years, female 6.4
GTEX-12WSM-0726-SM-5GCOW 60-69 years, male 6.3
GTEX-14C38-1526-SM-5RQJ7 50-59 years, male 6.3
GTEX-13FTZ-0726-SM-5IFFY 60-69 years, male 6.2
GTEX-YEC4-0826-SM-5P9FV 40-49 years, male 6.2
GTEX-13FTW-1126-SM-5J2NV 40-49 years, male 6.1
GTEX-RU72-1426-SM-46MUF 50-59 years, female 6.1
GTEX-1212Z-0226-SM-59HLF 60-69 years, male 5.9
GTEX-12WSL-0226-SM-5CVMJ 50-59 years, male 5.9
GTEX-T6MN-1226-SM-3NMA5 50-59 years, male 5.9
GTEX-WZTO-0626-SM-4PQYY 40-49 years, male 5.9
GTEX-Y5LM-0426-SM-4VBRO 40-49 years, female 5.9
GTEX-131XE-0326-SM-5LZVO 50-59 years, male 5.8
GTEX-X3Y1-2726-SM-4PQZH 40-49 years, male 5.8
GTEX-11NV4-1326-SM-5HL6V 60-69 years, male 5.7
GTEX-12WSI-0226-SM-5GCNA 50-59 years, male 5.7
GTEX-13NZB-0626-SM-5IFH6 30-39 years, male 5.7
GTEX-Q2AG-1126-SM-48U1P 40-49 years, female 5.7
GTEX-SJXC-1226-SM-4DM78 60-69 years, male 5.7
GTEX-WFON-1726-SM-4LVMQ 40-49 years, male 5.7
GTEX-12696-0826-SM-5EGGE 60-69 years, male 5.6
GTEX-YB5E-0326-SM-5IFHU 40-49 years, male 5.6
GTEX-11EQ9-0526-SM-5A5JZ 30-39 years, male 5.5
GTEX-13O3O-1826-SM-5IFGW 60-69 years, female 5.5
GTEX-13PVR-0126-SM-5S2PY 60-69 years, female 5.5
GTEX-14753-1626-SM-5NQ9L 60-69 years, male 5.5
GTEX-QESD-2026-SM-447BI 20-29 years, male 5.5
GTEX-RM2N-1926-SM-48FCU 50-59 years, male 5.5
GTEX-XOTO-0826-SM-4B65O 50-59 years, male 5.5
GTEX-11ZVC-0726-SM-5FQT9 50-59 years, female 5.4
GTEX-131XH-0626-SM-5LZWH 50-59 years, male 5.4
GTEX-1399T-0826-SM-5IFES 60-69 years, male 5.4
GTEX-139YR-0226-SM-5IFEM 50-59 years, male 5.4
GTEX-13OW6-2626-SM-5IFF2 50-59 years, male 5.4
GTEX-147JS-1126-SM-5RQIW 60-69 years, male 5.4
GTEX-ZPU1-0826-SM-57WG2 40-49 years, male 5.4
GTEX-ZVP2-0626-SM-51MSO 50-59 years, male 5.4
GTEX-14E1K-0326-SM-5S2PE 50-59 years, male 5.3
GTEX-TKQ2-1726-SM-4DXUP 50-59 years, male 5.3
GTEX-UPK5-1426-SM-4JBHH 40-49 years, male 5.3
GTEX-Z9EW-0426-SM-5CVM9 40-49 years, male 5.3
GTEX-1399R-1226-SM-5P9GF 30-39 years, male 5.2
GTEX-13FLV-0326-SM-5N9DJ 50-59 years, male 5.2
GTEX-145MO-2326-SM-5NQ9K 60-69 years, male 5.2
GTEX-14AS3-0126-SM-5Q5F4 40-49 years, female 5.2
GTEX-Q734-0326-SM-48U15 40-49 years, female 5.2
GTEX-ZF29-2026-SM-4WWB7 60-69 years, female 5.2
GTEX-ZZPU-0426-SM-5GZYH 50-59 years, female 5.2
GTEX-11OF3-0726-SM-5BC4Z 60-69 years, male 5.1
GTEX-12KS4-1326-SM-5LUB3 30-39 years, male 5.1
GTEX-PX3G-0826-SM-48TZS 20-29 years, female 5.1
GTEX-QEG4-1826-SM-4R1JN 30-39 years, male 5.1
GTEX-RWSA-1426-SM-47JXA 40-49 years, male 5.1
GTEX-11NUK-1226-SM-5P9GM 50-59 years, male 5.0
GTEX-11WQC-0726-SM-5EQMR 60-69 years, male 5.0
GTEX-YECK-1926-SM-4W21H 60-69 years, male 5.0
GTEX-145LU-1326-SM-5LU9N 50-59 years, male 4.9
GTEX-RTLS-1326-SM-46MUN 60-69 years, female 4.9
GTEX-RN64-1826-SM-48FDV 50-59 years, male 4.8
GTEX-131YS-1626-SM-5HL6C 60-69 years, female 4.7
GTEX-13VXU-0926-SM-5IFFH 50-59 years, male 4.7
GTEX-UTHO-2426-SM-4JBHD 60-69 years, male 4.7
GTEX-VUSG-0126-SM-4KL1X 50-59 years, male 4.7
GTEX-12WSD-1426-SM-5GCN9 60-69 years, female 4.6
GTEX-ZAB5-0426-SM-5CVMI 50-59 years, male 4.6
GTEX-ZVT4-0626-SM-5E45T 50-59 years, female 4.6
GTEX-14DAQ-1726-SM-5S2R2 60-69 years, female 4.5
GTEX-QV44-0326-SM-4R1KD 50-59 years, male 4.5
GTEX-144GM-1326-SM-5LU5E 20-29 years, male 4.4
GTEX-ZF2S-3026-SM-4WWCH 50-59 years, female 4.4
GTEX-11GSP-0626-SM-5986T 60-69 years, female 4.3
GTEX-RNOR-1426-SM-48FDJ 50-59 years, female 4.3
GTEX-ZYY3-0626-SM-5NQ6W 60-69 years, female 4.3
GTEX-11DXY-0526-SM-5EGGQ 60-69 years, male 4.2
GTEX-13112-1426-SM-5EGH8 50-59 years, male 4.2
GTEX-X4EP-1026-SM-4QAS5 60-69 years, female 4.2
GTEX-ZTPG-1426-SM-51MT3 20-29 years, female 4.2
GTEX-ZYT6-0626-SM-5E45V 30-39 years, male 4.1
GTEX-11ZTS-1426-SM-5EQMM 60-69 years, female 4.0
GTEX-WYVS-1926-SM-4PQZ2 40-49 years, female 4.0
GTEX-11DXZ-0126-SM-5EGGY 50-59 years, male 3.7
GTEX-11ZUS-2526-SM-59872 30-39 years, male 3.7
GTEX-U3ZN-0226-SM-3DB8D 30-39 years, female 3.6
GTEX-ZAB4-0826-SM-5LU9D 40-49 years, male 3.5
GTEX-12ZZZ-1326-SM-59HKW 60-69 years, male 2.6
Show all

LIVER - FANTOM5 CAGEi

Tissue data obtained through Cap Analysis of Gene Expression (CAGE) are reported as Tags Per Million, generated by the FANTOM5 project. More information can be found here.

Read more

Average Tags Per Million

39.7

FANTOM5 sample id

Sample description

Tags Per Million

Liver
Tags Per Million: 39.7
FF:10018-101C9 64,69,70 years, mixed 39.7

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