DictionaryProtein expressionVimVim - Detail 1
Vim
High magnification of melanoma (SSM) in skin showing the expression of vimentin (VIM). Cytoplasmic positivity for vimentin is seen in tumor cells. Epidermal keratinocytes are negative.
Vimentin (VIM) - Marker for mesenchymal cells
Vimentin is an intermediate filament protein ubiquitously expressed mesenchymal cells, and is therefore used clinically to identify mesenchyme and sarcoma tumors. The function of vimentin is to provide cellular integrity and cell shape by supporting and anchoring organelles within the cytoplasm.
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