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MTMR7

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GENERAL INFORMATION

Gene name

 MTMR7

Gene description

 Myotubularin related protein 7

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

Summary

RNA cell category

 Cell line enhanced (SCLC-21H, SH-SY5Y)

Protein evidence

 Evidence at protein level

Main location

 Not available

DATA RELIABILITY

Reliability score

 Pending cell analysis.

ASSAYS
RNA expression

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (SCLC-21H, SH-SY5Y)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

GENE INFORMATION

Gene name

 MTMR7

Synonyms

Description

 Myotubularin related protein 7 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the myotubularin family of tyrosine/dual-specificity phosphatases. The encoded protein is characterized by four distinct domains that are conserved among all members of the myotubularin family: the glucosyltransferase, Rab-like GTPase activator and myotubularins domain, the Rac-induced recruitment domain, the protein tyrosine phosphatases and dual-specificity phosphatases domain and the suppressor of variegation 3-9, enhancer-of-zeste, and trithorax interaction domain. This protein dephosphorylates the target substrates phosphatidylinositol 3-phosphate and inositol 1,3-bisphosphate. A pseudogene of this gene is found on chromosome 5. [provided by RefSeq, Mar 2009]

Chromosome

 8

Cytoband

 p22

Chromosome location (bp)

 17298030 - 17413528

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000003987 (version 83.38)

Entrez gene

 9108

UniProt

 Q9Y216 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9Y216

Antibodypedia

 MTMR7 antibodies

PROTEIN BROWSER
MTMR7-001
MTMR7-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
MTMR7-001
ENSP00000180173
ENST00000180173
Q9Y216 [Direct mapping]
Myotubularin-related protein 7
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Show all
GO:0004725 [protein tyrosine phosphatase activity]
GO:0005515 [protein binding]
GO:0005829 [cytosol]
GO:0006470 [protein dephosphorylation]
GO:0006644 [phospholipid metabolic process]
GO:0006661 [phosphatidylinositol biosynthetic process]
GO:0016020 [membrane]
GO:0016311 [dephosphorylation]
GO:0016791 [phosphatase activity]
GO:0035335 [peptidyl-tyrosine dephosphorylation]
GO:0044281 [small molecule metabolic process]
GO:0046855 [inositol phosphate dephosphorylation]
GO:0046856 [phosphatidylinositol dephosphorylation]
GO:0052866 [phosphatidylinositol phosphate phosphatase activity]
Show all
 660 aa
75.8 kDa 		No 0
MTMR7-002
ENSP00000429733
ENST00000521857
Q9Y216 [Direct mapping]
Myotubularin-related protein 7
Show all
Predicted intracellular proteins
Show all
GO:0004725 [protein tyrosine phosphatase activity]
GO:0005515 [protein binding]
GO:0005829 [cytosol]
GO:0006470 [protein dephosphorylation]
GO:0006644 [phospholipid metabolic process]
GO:0006661 [phosphatidylinositol biosynthetic process]
GO:0016311 [dephosphorylation]
GO:0016791 [phosphatase activity]
GO:0035335 [peptidyl-tyrosine dephosphorylation]
GO:0044281 [small molecule metabolic process]
GO:0052866 [phosphatidylinositol phosphate phosphatase activity]
Show all
 555 aa
64.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.