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MEOX1

GENERAL INFORMATION

Gene name

 MEOX1

Gene description

 Mesenchyme homeobox 1

Protein class

 Disease related genes
Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (adipose tissue)
GTEx:Tissue enhanced (adipose tissue, breast)
FANTOM5:Mixed

Protein evidence

 Evidence at protein level

Protein expression

 Nuclear and cytoplasmic expression in several tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Pending external verification.

Reliability score

 Uncertain based on 1 antibody.
HPA045214
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Cerebellum

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (adipose tissue)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (adipose tissue, breast)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed

GENE INFORMATION

Gene name

 MEOX1 (HGNC Symbol)

Synonyms

 MOX1

Description

 Mesenchyme homeobox 1 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the molecular signaling network regulating somite development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Chromosome

 17

Cytoband

 q21.31

Chromosome location (bp)

 43640388 - 43661954

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000005102 (version 83.38)

Entrez gene

 4222

UniProt

 P50221 (UniProt - Evidence at protein level)

neXtProt

 NX_P50221

Antibodypedia

 MEOX1 antibodies

PROTEIN BROWSER
MEOX1-001
MEOX1-002
MEOX1-003
MEOX1-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
MEOX1-001
ENSP00000321684
ENST00000318579
P50221 [Direct mapping]
Homeobox protein MOX-1
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Predicted intracellular proteins
Transcription factors
   Helix-turn-helix domains
Disease related genes
Show all
GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding]
GO:0001046 [core promoter sequence-specific DNA binding]
GO:0001077 [transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding]
GO:0001757 [somite specification]
GO:0003674 [molecular_function]
GO:0003677 [DNA binding]
GO:0003682 [chromatin binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0007275 [multicellular organismal development]
GO:0008150 [biological_process]
GO:0043565 [sequence-specific DNA binding]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0060218 [hematopoietic stem cell differentiation]
GO:0061053 [somite development]
GO:0061056 [sclerotome development]
GO:0071837 [HMG box domain binding]
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 254 aa
28 kDa 		No 0
MEOX1-002
ENSP00000449049
ENST00000549132
F8VXS6 [Direct mapping]
Homeobox protein MOX-1
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Predicted intracellular proteins
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GO:0003677 [DNA binding]
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 167 aa
18.5 kDa 		No 0
MEOX1-003
ENSP00000377271
ENST00000393661
P50221 [Direct mapping]
Homeobox protein MOX-1
Show all
Predicted intracellular proteins
Transcription factors
   Helix-turn-helix domains
Disease related genes
Show all
GO:0001046 [core promoter sequence-specific DNA binding]
GO:0003674 [molecular_function]
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007275 [multicellular organismal development]
GO:0008150 [biological_process]
GO:0043565 [sequence-specific DNA binding]
GO:0060218 [hematopoietic stem cell differentiation]
GO:0061053 [somite development]
GO:0061056 [sclerotome development]
Show all
 139 aa
15.6 kDa 		No 0
MEOX1-201
ENSP00000328678
ENST00000329168
P50221 [Direct mapping]
Homeobox protein MOX-1
Show all
Predicted intracellular proteins
Transcription factors
   Helix-turn-helix domains
Disease related genes
Show all
GO:0001046 [core promoter sequence-specific DNA binding]
GO:0003674 [molecular_function]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0007275 [multicellular organismal development]
GO:0008150 [biological_process]
GO:0043565 [sequence-specific DNA binding]
GO:0060218 [hematopoietic stem cell differentiation]
GO:0061053 [somite development]
GO:0061056 [sclerotome development]
Show all
 184 aa
19.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.