Expression of FAM214B in cancer - Summary - The Human Protein Atlas

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FAM214B

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	FAM214B
Gene description	Family with sequence similarity 214, member B
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	7
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Mixed
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in many tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 2 antibodies. HPA048831 , HPA055751
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA048831	HPA055751

GENE INFORMATION
Gene name	FAM214B (HGNC Symbol)
Synonyms	bA182N22.6, FLJ11560, KIAA1539
Description	Family with sequence similarity 214, member B (HGNC Symbol)
Entrez gene summary
Chromosome	9
Cytoband	p13.3
Chromosome location (bp)	35104112 - 35116341
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000005238 (version 83.38)
Entrez gene	80256
UniProt	Q7L5A3 (UniProt - Evidence at protein level)
neXtProt	NX_Q7L5A3
Antibodypedia	FAM214B antibodies

PROTEIN BROWSER

FAM214B-001	FAM214B-002	FAM214B-003	FAM214B-005	FAM214B-013	FAM214B-014	FAM214B-015

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FAM214B-001 ENSP00000367823 ENST00000378561	Q7L5A3 [Direct mapping] Protein FAM214B Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] Show all	538 aa 56.7 kDa	No	0
FAM214B-002 ENSP00000367829 ENST00000378566	Q7L5A3 [Direct mapping] Protein FAM214B Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] Show all	233 aa 25.7 kDa	No	0
FAM214B-003 ENSP00000319897 ENST00000322813	Q7L5A3 [Direct mapping] Protein FAM214B Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] Show all	538 aa 56.7 kDa	No	0
FAM214B-005 ENSP00000367819 ENST00000378557	Q7L5A3 [Direct mapping] Protein FAM214B Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] Show all	538 aa 56.7 kDa	No	0
FAM214B-013 ENSP00000474833 ENST00000605244	Q7L5A3 [Direct mapping] Protein FAM214B Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] Show all	538 aa 56.7 kDa	No	0
FAM214B-014 ENSP00000475120 ENST00000488109	Q7L5A3 [Direct mapping] Protein FAM214B Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] Show all	538 aa 56.7 kDa	No	0
FAM214B-015 ENSP00000474335 ENST00000603301	Q7L5A3 [Direct mapping] Protein FAM214B Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] Show all	538 aa 56.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.