We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
Rare case of glioma and melanoma displayed moderate nuclear positivity. Remaining cancer tissues were weakly stained or negative.
GENE INFORMATION
Gene name
SOX8
Synonyms
Description
SRY (sex determining region Y)-box 8 (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome). [provided by RefSeq, Jul 2008]