Expression of C19orf60 in cancer - Summary - The Human Protein Atlas

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C19orf60

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	C19orf60
Gene description	Chromosome 19 open reading frame 60
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Cell line enhanced (PC-3)
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic and membranous expression in most tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA043414
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PROGNOSTIC SUMMARY
Prognostic marker in urothelial cancer (favourable).
Urothelial cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA043414

GENE INFORMATION
Gene name	C19orf60 (HGNC Symbol)
Synonyms	FLJ20850, FLJ30108, FLJ34606, FLJ37391
Description	Chromosome 19 open reading frame 60 (HGNC Symbol)
Entrez gene summary
Chromosome	19
Cytoband	p13.11
Chromosome location (bp)	18588685 - 18592336
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000006015 (version 83.38)
Entrez gene	55049
UniProt	Q96EN9 (UniProt - Evidence at protein level)
neXtProt	NX_Q96EN9
Antibodypedia	C19orf60 antibodies

PROTEIN BROWSER

C19orf60-001	C19orf60-002	C19orf60-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C19orf60-001 ENSP00000351422 ENST00000358607	Q96EN9 [Direct mapping] Uncharacterized protein C19orf60 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	201 aa 22.6 kDa	No	0
C19orf60-002 ENSP00000398467 ENST00000450195	Q96EN9 [Direct mapping] Uncharacterized protein C19orf60 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	179 aa 20.1 kDa	No	0
C19orf60-005 ENSP00000469859 ENST00000595490	M0QYI9 [Direct mapping] Uncharacterized protein C19orf60 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		60 aa 6.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.