Expression of KIAA0100 in cancer - Summary - The Human Protein Atlas

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KIAA0100

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	KIAA0100
Gene description	KIAA0100
Protein class	Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in several different tissue types.

ANTIBODY IHC RELIABILITY
Data reliability description	Pending external verification. Secreted protein, tissue location of RNA and protein might differ and correlation is complex.
Reliability score	Uncertain based on 1 antibody. HPA042781
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PROGNOSTIC SUMMARY
Prognostic marker in liver cancer (unfavourable).
Liver cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA042781

GENE INFORMATION
Gene name	KIAA0100 (HGNC Symbol)
Synonyms	BCOX, BCOX1, CT101, DKFZp686M0843, MGC111488
Description	KIAA0100 (HGNC Symbol)
Entrez gene summary
Chromosome	17
Cytoband	q11.2
Chromosome location (bp)	28614440 - 28645454
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000007202 (version 83.38)
Entrez gene	9703
UniProt	Q14667 (UniProt - Evidence at protein level)
neXtProt	NX_Q14667
Antibodypedia	KIAA0100 antibodies

PROTEIN BROWSER

KIAA0100-001	KIAA0100-002	KIAA0100-011	KIAA0100-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
KIAA0100-001 ENSP00000436773 ENST00000528896	Q14667 [Direct mapping] Protein KIAA0100 Show all	MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005576 [extracellular region] Show all	2235 aa 253.7 kDa	Yes	0
KIAA0100-002 ENSP00000467716 ENST00000389003	K7EQ86 [Direct mapping] KIAA0100, isoform CRA_a; Protein KIAA0100 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		2092 aa 237.3 kDa	No	0
KIAA0100-011 ENSP00000467944 ENST00000577261	K7EQR3 [Direct mapping] Protein KIAA0100 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		287 aa 33.2 kDa	No	0
KIAA0100-201 ENSP00000446443 ENST00000544884	Q08E86 [Direct mapping] KIAA0100 protein; Protein KIAA0100 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	2092 aa 237.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.