Expression of CRAMP1 in cancer - Summary

GENERAL INFORMATION
Gene name	CRAMP1
Gene description	Cramped chromatin regulator homolog 1
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic and nuclear expression in several different tissue types, most abundant in Leydig cells.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA041752
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PROGNOSTIC SUMMARY
Prognostic marker in stomach cancer (favourable).
Stomach cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

STAINING SUMMARY

HPA041752

GENE INFORMATION
Gene name	CRAMP1 (HGNC Symbol)
Synonyms	CRAMP1L, KIAA1426
Description	Cramped chromatin regulator homolog 1 (HGNC Symbol)
Entrez gene summary
Chromosome	16
Cytoband	p13.3
Chromosome location (bp)	1612325 - 1677908
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000007545 (version 83.38)
Entrez gene	57585
UniProt	Q96RY5 (UniProt - Evidence at protein level)
neXtProt	NX_Q96RY5
Antibodypedia	CRAMP1 antibodies

PROTEIN BROWSER

CRAMP1-001	CRAMP1-006	CRAMP1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CRAMP1-001 ENSP00000380559 ENST00000397412	Q96RY5 [Direct mapping] Protein cramped-like Show all	Predicted intracellular proteins Transcription factors Helix-turn-helix domains Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] Show all	1269 aa 134.7 kDa	No	0
CRAMP1-006 ENSP00000399172 ENST00000415022	H7C194 [Direct mapping] Protein cramped-like Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		184 aa 19.1 kDa	No	0
CRAMP1-201 ENSP00000293925 ENST00000293925	Q96RY5 [Direct mapping] Protein cramped-like Show all	Predicted intracellular proteins Transcription factors Helix-turn-helix domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] Show all	1269 aa 134.7 kDa	No	0