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TFAP2D

GENERAL INFORMATION

Gene name

 TFAP2D

Gene description

 Transcription factor AP-2 delta (activating enhancer binding protein 2 delta)

Protein class

 Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Tissue enriched (lung cancer)
HPA (cell line):Not detected
HPA (normal tissue):Not detected

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY

Data reliability
description

 RNA-based expert annotation gave inconclusive results. No RNA expression data detected and pending external verification.

Reliability score

 Uncertain based on 1 antibody.
HPA048962
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Tissue enriched (lung cancer)

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA048962

GENE INFORMATION

Gene name

 TFAP2D (HGNC Symbol)

Synonyms

 TFAP2BL1

Description

 Transcription factor AP-2 delta (activating enhancer binding protein 2 delta) (HGNC Symbol)

Entrez gene summary

Chromosome

 6

Cytoband

 p12.3

Chromosome location (bp)

 50713828 - 50772988

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000008197 (version 83.38)

Entrez gene

 83741

UniProt

 Q7Z6R9 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q7Z6R9

Antibodypedia

 TFAP2D antibodies

PROTEIN BROWSER
TFAP2D-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
TFAP2D-001
ENSP00000008391
ENST00000008391
Q7Z6R9 [Direct mapping]
Transcription factor AP-2-delta
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   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Transcription factors
   Basic domains
Protein evidence (Kim et al 2014)
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GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding]
GO:0000981 [RNA polymerase II transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005667 [transcription factor complex]
GO:0006351 [transcription, DNA-templated]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0042127 [regulation of cell proliferation]
GO:0043524 [negative regulation of neuron apoptotic process]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0048856 [anatomical structure development]
GO:0061379 [inferior colliculus development]
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 452 aa
49.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.