Expression of HEATR5B in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

HEATR5B

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	HEATR5B
Gene description	HEAT repeat containing 5B
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

General nuclear and cytoplasmic expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Approved based on 1 antibody. HPA042025
	SHOW MORE

PROGNOSTIC SUMMARY
Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA042025

GENE INFORMATION
Gene name	HEATR5B (HGNC Symbol)
Synonyms	DKFZp686P15184, KIAA1414
Description	HEAT repeat containing 5B (HGNC Symbol)
Entrez gene summary
Chromosome	2
Cytoband	p22.2
Chromosome location (bp)	36968383 - 37084342
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000008869 (version 83.38)
Entrez gene	54497
UniProt	Q9P2D3 (UniProt - Evidence at protein level)
neXtProt	NX_Q9P2D3
Antibodypedia	HEATR5B antibodies

PROTEIN BROWSER

HEATR5B-001	HEATR5B-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
HEATR5B-001 ENSP00000233099 ENST00000233099	Q9P2D3 [Direct mapping] HEAT repeat-containing protein 5B Show all	SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005488 [binding] GO:0005515 [protein binding] GO:0016020 [membrane] GO:0070062 [extracellular exosome] Show all	2071 aa 224.3 kDa	No	0
HEATR5B-006 ENSP00000408222 ENST00000425467	H7C2X3 [Direct mapping] HEAT repeat-containing protein 5B Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		115 aa 12.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.