Expression of RWDD2A in cancer - Summary - The Human Protein Atlas

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RWDD2A

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	RWDD2A
Gene description	RWD domain containing 2A
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Mixed
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic and nuclear expression in several tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data.
Reliability score	Uncertain based on 3 antibodies. HPA030105 , HPA030106 , HPA030107
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PROGNOSTIC SUMMARY
Prognostic marker in ovarian cancer (favourable), pancreatic cancer (favourable) and glioma (favourable).
Ovarian cancer p<0.001 Pancreatic cancer p<0.001 Glioma p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA030105	HPA030106	HPA030107

GENE INFORMATION
Gene name	RWDD2A (HGNC Symbol)
Synonyms	dJ747H23.2, MGC13523, RWDD2
Description	RWD domain containing 2A (HGNC Symbol)
Entrez gene summary
Chromosome	6
Cytoband	q14.1
Chromosome location (bp)	83193379 - 83198932
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000013392 (version 83.38)
Entrez gene	112611
UniProt	Q9UIY3 (UniProt - Evidence at protein level)
neXtProt	NX_Q9UIY3
Antibodypedia	RWDD2A antibodies

PROTEIN BROWSER

RWDD2A-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RWDD2A-001 ENSP00000358739 ENST00000369724	Q9UIY3 [Direct mapping] RWD domain-containing protein 2A Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	292 aa 33.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.