Expression of AQR in cancer - Summary - The Human Protein Atlas

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AQR

TISSUE

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CELL

PATHOLOGY

GENERAL INFORMATION
Gene name	AQR
Gene description	Aquarius intron-binding spliceosomal factor
Protein class	Plasma proteins Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

ANTIBODY IHC RELIABILITY
Reliability score	Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable).
Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Pending cancer tissue analysis
STAINING SUMMARY

GENE INFORMATION
Gene name	AQR (HGNC Symbol)
Synonyms	fSAP164, IBP160, KIAA0560
Description	Aquarius intron-binding spliceosomal factor (HGNC Symbol)
Entrez gene summary
Chromosome	15
Cytoband	q14
Chromosome location (bp)	34851782 - 34969839
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000021776 (version 83.38)
Entrez gene	9716
UniProt	O60306 (UniProt - Evidence at protein level)
neXtProt	NX_O60306
Antibodypedia	AQR antibodies

PROTEIN BROWSER

AQR-001	AQR-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
AQR-001 ENSP00000156471 ENST00000156471	O60306 [Direct mapping] Intron-binding protein aquarius A0A024R9L1 [Target identity:100%; Query identity:100%] Aquarius homolog (Mouse), isoform CRA_b Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000398 [mRNA splicing, via spliceosome] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005681 [spliceosomal complex] GO:0006281 [DNA repair] GO:0006283 [transcription-coupled nucleotide-excision repair] GO:0006289 [nucleotide-excision repair] GO:0016020 [membrane] GO:0044822 [poly(A) RNA binding] GO:0071013 [catalytic step 2 spliceosome] Show all	1485 aa 171.3 kDa	No	0
AQR-004 ENSP00000453278 ENST00000560117	H0YLN9 [Direct mapping] Intron-binding protein aquarius Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0000398 [mRNA splicing, via spliceosome] GO:0005681 [spliceosomal complex] Show all	180 aa 21.1 kDa	No	1

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.