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DERA

GENERAL INFORMATION

Gene name

 DERA

Gene description

 Deoxyribose-phosphate aldolase (putative)

Protein class

 Enzymes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 6
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

ANTIBODY IHC RELIABILITY

Reliability score

 Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Prognostic marker in thyroid cancer (favourable) and pancreatic cancer (unfavourable).
Thyroid cancer p<0.001
Pancreatic cancer p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Pending cancer tissue analysis

STAINING SUMMARY

 

GENE INFORMATION

Gene name

 DERA (HGNC Symbol)

Synonyms

 CGI-26, DEOC

Description

 Deoxyribose-phosphate aldolase (putative) (HGNC Symbol)

Entrez gene summary

Chromosome

 12

Cytoband

 p12.3

Chromosome location (bp)

 15911172 - 16037282

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000023697 (version 83.38)

Entrez gene

 51071

UniProt

 Q9Y315 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9Y315

Antibodypedia

 DERA antibodies

PROTEIN BROWSER
DERA-001
DERA-003
DERA-004
DERA-006
DERA-007
DERA-008

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
DERA-001
ENSP00000416583
ENST00000428559
Q9Y315 [Direct mapping]
Deoxyribose-phosphate aldolase
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Enzymes
   ENZYME proteins
   Lyases
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004139 [deoxyribose-phosphate aldolase activity]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0009264 [deoxyribonucleotide catabolic process]
GO:0016052 [carbohydrate catabolic process]
GO:0016829 [lyase activity]
GO:0046121 [deoxyribonucleoside catabolic process]
GO:0046386 [deoxyribose phosphate catabolic process]
GO:0070062 [extracellular exosome]
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 318 aa
35.2 kDa 		No 0
DERA-003
ENSP00000431757
ENST00000526530
G3V158 [Direct mapping]
2-deoxyribose-5-phosphate aldolase homolog (C. elegans), isoform CRA_a; Deoxyribose-phosphate aldolase
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004139 [deoxyribose-phosphate aldolase activity]
GO:0005737 [cytoplasm]
GO:0009264 [deoxyribonucleotide catabolic process]
GO:0016052 [carbohydrate catabolic process]
GO:0016829 [lyase activity]
Show all
 230 aa
25.1 kDa 		No 0
DERA-004
ENSP00000432633
ENST00000524480
E9PPK3 [Direct mapping]
Deoxyribose-phosphate aldolase
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004139 [deoxyribose-phosphate aldolase activity]
GO:0005737 [cytoplasm]
GO:0009264 [deoxyribonucleotide catabolic process]
GO:0016052 [carbohydrate catabolic process]
GO:0016829 [lyase activity]
Show all
 98 aa
10.5 kDa 		No 0
DERA-006
ENSP00000433051
ENST00000531803
E9PML7 [Direct mapping]
Deoxyribose-phosphate aldolase
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004139 [deoxyribose-phosphate aldolase activity]
GO:0005737 [cytoplasm]
GO:0009264 [deoxyribonucleotide catabolic process]
GO:0016052 [carbohydrate catabolic process]
GO:0016829 [lyase activity]
Show all
 236 aa
26 kDa 		No 0
DERA-007
ENSP00000436999
ENST00000532964
E9PPM8 [Direct mapping]
Deoxyribose-phosphate aldolase
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   SCAMPI predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004139 [deoxyribose-phosphate aldolase activity]
GO:0005737 [cytoplasm]
GO:0009264 [deoxyribonucleotide catabolic process]
GO:0016052 [carbohydrate catabolic process]
GO:0016829 [lyase activity]
Show all
 275 aa
30.5 kDa 		No 0
DERA-008
ENSP00000434973
ENST00000533447
E9PMH9 [Direct mapping]
Deoxyribose-phosphate aldolase
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004139 [deoxyribose-phosphate aldolase activity]
GO:0005737 [cytoplasm]
GO:0009264 [deoxyribonucleotide catabolic process]
GO:0016052 [carbohydrate catabolic process]
GO:0016829 [lyase activity]
Show all
 163 aa
17.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.