Fields »
ABOUT
HELP
BLOG
DEPDC1

GENERAL INFORMATION

Gene name

 DEPDC1

Gene description

 DEP domain containing 1

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (testis)
GTEx:Group enriched (esophagus, testis)
FANTOM5:Tissue enhanced (appendix, testis)

Protein evidence

 Evidence at protein level

Protein expression

 Nuclear expression in several tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Pending external verification.

Reliability score

 Approved based on 1 antibody.
CAB017845
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (testis)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (esophagus, testis)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (appendix, testis)

GENE INFORMATION

Gene name

 DEPDC1 (HGNC Symbol)

Synonyms

 DEP.8, DEPDC1A, FLJ20354, SDP35

Description

 DEP domain containing 1 (HGNC Symbol)

Entrez gene summary

Chromosome

 1

Cytoband

 p31.3

Chromosome location (bp)

 68474152 - 68497221

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000024526 (version 83.38)

Entrez gene

 55635

UniProt

 Q5TB30 (UniProt - Evidence at protein level)

neXtProt

 NX_Q5TB30

Antibodypedia

 DEPDC1 antibodies

PROTEIN BROWSER
DEPDC1-001
DEPDC1-002
DEPDC1-004

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
DEPDC1-001
ENSP00000360005
ENST00000370966
Q5TB30 [Direct mapping]
DEP domain-containing protein 1A
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005096 [GTPase activator activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0007165 [signal transduction]
GO:0017053 [transcriptional repressor complex]
GO:0035556 [intracellular signal transduction]
GO:0043547 [positive regulation of GTPase activity]
GO:0045892 [negative regulation of transcription, DNA-templated]
Show all
 527 aa
61.5 kDa 		No 0
DEPDC1-002
ENSP00000412292
ENST00000456315
Q5TB30 [Direct mapping]
DEP domain-containing protein 1A
Show all
   MEMSAT3 predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005096 [GTPase activator activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0007165 [signal transduction]
GO:0017053 [transcriptional repressor complex]
GO:0035556 [intracellular signal transduction]
GO:0043547 [positive regulation of GTPase activity]
GO:0045892 [negative regulation of transcription, DNA-templated]
Show all
 811 aa
93 kDa 		No 0
DEPDC1-004
ENSP00000431477
ENST00000525124
E9PL61 [Direct mapping]
DEP domain-containing protein 1A
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 34 aa
3.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.