Fields »
ABOUT
HELP
BLOG
IFT88

Please wait until image is loaded before changing channels

GENERAL INFORMATION

Gene name

 IFT88

Gene description

 Intraflagellar transport 88

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 4
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

Summary

RNA cell category

 Expressed in all

Protein evidence

 Evidence at protein level

Main location

 Not available

DATA RELIABILITY

Reliability score

 Pending cell analysis.

ASSAYS
RNA expression

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

GENE INFORMATION

Gene name

 IFT88 (HGNC Symbol)

Synonyms

 D13S1056E, hTg737, MGC26259, Tg737, TTC10

Description

 Intraflagellar transport 88 (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the tetratrico peptide repeat (TPR) family. Mutations of a similar gene in mouse can cause polycystic kidney disease. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Chromosome

 13

Cytoband

 q12.11

Chromosome location (bp)

 20567069 - 20691437

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000032742 (version 83.38)

Entrez gene

 8100

UniProt

 Q13099 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q13099

Antibodypedia

 IFT88 antibodies

PROTEIN BROWSER
IFT88-001
IFT88-002
IFT88-004
IFT88-007

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
IFT88-001
ENSP00000261632
ENST00000351808
Q13099 [Direct mapping]
Intraflagellar transport protein 88 homolog
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005814 [centriole]
GO:0005929 [cilium]
GO:0006996 [organelle organization]
GO:0030992 [intraciliary transport particle B]
GO:0031514 [motile cilium]
GO:0036064 [ciliary basal body]
GO:0060271 [cilium morphogenesis]
GO:0072372 [primary cilium]
GO:0097542 [ciliary tip]
GO:1902017 [regulation of cilium assembly]
GO:2000785 [regulation of autophagosome assembly]
Show all
 824 aa
93.2 kDa 		No 0
IFT88-002
ENSP00000323580
ENST00000319980
Q13099 [Direct mapping]
Intraflagellar transport protein 88 homolog
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001654 [eye development]
GO:0001822 [kidney development]
GO:0001889 [liver development]
GO:0002080 [acrosomal membrane]
GO:0003382 [epithelial cell morphogenesis]
GO:0005515 [protein binding]
GO:0005813 [centrosome]
GO:0005814 [centriole]
GO:0005929 [cilium]
GO:0005930 [axoneme]
GO:0006996 [organelle organization]
GO:0007219 [Notch signaling pathway]
GO:0007224 [smoothened signaling pathway]
GO:0007288 [sperm axoneme assembly]
GO:0007290 [spermatid nucleus elongation]
GO:0007368 [determination of left/right symmetry]
GO:0007399 [nervous system development]
GO:0007420 [brain development]
GO:0007507 [heart development]
GO:0008104 [protein localization]
GO:0008544 [epidermis development]
GO:0008589 [regulation of smoothened signaling pathway]
GO:0009887 [organ morphogenesis]
GO:0009952 [anterior/posterior pattern specification]
GO:0009953 [dorsal/ventral pattern formation]
GO:0019894 [kinesin binding]
GO:0021513 [spinal cord dorsal/ventral patterning]
GO:0021537 [telencephalon development]
GO:0030324 [lung development]
GO:0030992 [intraciliary transport particle B]
GO:0031016 [pancreas development]
GO:0031122 [cytoplasmic microtubule organization]
GO:0031512 [motile primary cilium]
GO:0031514 [motile cilium]
GO:0032391 [photoreceptor connecting cilium]
GO:0034405 [response to fluid shear stress]
GO:0035058 [nonmotile primary cilium assembly]
GO:0036064 [ciliary basal body]
GO:0036334 [epidermal stem cell homeostasis]
GO:0042384 [cilium assembly]
GO:0042487 [regulation of odontogenesis of dentin-containing tooth]
GO:0042733 [embryonic digit morphogenesis]
GO:0043568 [positive regulation of insulin-like growth factor receptor signaling pathway]
GO:0045598 [regulation of fat cell differentiation]
GO:0048853 [forebrain morphogenesis]
GO:0050680 [negative regulation of epithelial cell proliferation]
GO:0055007 [cardiac muscle cell differentiation]
GO:0060021 [palate development]
GO:0060091 [kinocilium]
GO:0060122 [inner ear receptor stereocilium organization]
GO:0060173 [limb development]
GO:0060259 [regulation of feeding behavior]
GO:0060271 [cilium morphogenesis]
GO:0060411 [cardiac septum morphogenesis]
GO:0060426 [lung vasculature development]
GO:0060914 [heart formation]
GO:0061351 [neural precursor cell proliferation]
GO:0070613 [regulation of protein processing]
GO:0072372 [primary cilium]
GO:0090102 [cochlea development]
GO:0097541 [axonemal basal plate]
GO:0097542 [ciliary tip]
GO:0097546 [ciliary base]
GO:1902017 [regulation of cilium assembly]
GO:2000785 [regulation of autophagosome assembly]
Show all
 833 aa
94.3 kDa 		No 0
IFT88-004
ENSP00000437719
ENST00000537103
F5H6C2 [Direct mapping]
Intraflagellar transport protein 88 homolog
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
Show all
 368 aa
41.9 kDa 		No 0
IFT88-007
ENSP00000374024
ENST00000389373
F6SRW8 [Direct mapping]
Intraflagellar transport protein 88 homolog
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 50 aa
5.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.