Expression of MFAP3 in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

MFAP3

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	MFAP3
Gene description	Microfibrillar-associated protein 3
Protein class	Predicted intracellular proteins Predicted membrane proteins Predicted secreted proteins
Predicted localization	Intracellular,Membrane,Secreted
Number of transcripts	5
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

General cytoplasmic expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Approved based on 1 antibody. HPA015883
	SHOW MORE

PROGNOSTIC SUMMARY
Prognostic marker in cervical cancer (unfavourable).
Cervical cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA015883

GENE INFORMATION
Gene name	MFAP3
Synonyms
Description	Microfibrillar-associated protein 3 (HGNC Symbol)
Entrez gene summary
Chromosome	5
Cytoband	q33.2
Chromosome location (bp)	154038906 - 154220478
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000037749 (version 83.38)
Entrez gene	4238
UniProt	P55082 (UniProt - Evidence at transcript level)
neXtProt	NX_P55082
Antibodypedia	MFAP3 antibodies

PROTEIN BROWSER

MFAP3-001	MFAP3-002	MFAP3-003	MFAP3-004	MFAP3-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MFAP3-001 ENSP00000322956 ENST00000322602	P55082 [Direct mapping] Microfibril-associated glycoprotein 3 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005576 [extracellular region] GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] GO:0030198 [extracellular matrix organization] Show all	362 aa 40.2 kDa	Yes	1
MFAP3-002 ENSP00000430852 ENST00000522782	E5RHQ6 [Direct mapping] Microfibril-associated glycoprotein 3 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	123 aa 13.6 kDa	Yes	0
MFAP3-003 ENSP00000414219 ENST00000439768	P55082 [Direct mapping] Microfibril-associated glycoprotein 3 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005576 [extracellular region] GO:0005886 [plasma membrane] GO:0016021 [integral component of membrane] GO:0030198 [extracellular matrix organization] Show all	216 aa 24.1 kDa	No	0
MFAP3-004 ENSP00000430602 ENST00000522177	E5RJ59 [Direct mapping] Microfibril-associated glycoprotein 3 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all		109 aa 12 kDa	Yes	0
MFAP3-005 ENSP00000430007 ENST00000520899	E5RH26 [Direct mapping] Microfibril-associated glycoprotein 3 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		17 aa 1.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.