Expression of RAI14 in cancer - Summary - The Human Protein Atlas

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RAI14

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TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	RAI14
Gene description	Retinoic acid induced 14
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	14
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Mixed
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Membranous and cytoplasmic expression in several tissues, most abundant in placenta.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Supported based on 2 antibodies. HPA036949 , HPA036950
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PROGNOSTIC SUMMARY
Prognostic marker in stomach cancer (unfavourable) and renal cancer (unfavourable).
Stomach cancer p<0.001 Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA036949	HPA036950

GENE INFORMATION
Gene name	RAI14 (HGNC Symbol)
Synonyms	DKFZp564G013, KIAA1334, NORPEG, RAI13
Description	Retinoic acid induced 14 (HGNC Symbol)
Entrez gene summary
Chromosome	5
Cytoband	p13.2
Chromosome location (bp)	34656237 - 34832627
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000039560 (version 83.38)
Entrez gene	26064
UniProt	Q9P0K7 (UniProt - Evidence at protein level)
neXtProt	NX_Q9P0K7
Antibodypedia	RAI14 antibodies

PROTEIN BROWSER

RAI14-001	RAI14-002	RAI14-003	RAI14-005	RAI14-006	RAI14-007	RAI14-008	RAI14-009	RAI14-010	RAI14-011	RAI14-014	RAI14-015	RAI14-017	RAI14-022

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RAI14-001 ENSP00000388725 ENST00000428746	Q9P0K7 [Direct mapping] Ankycorbin Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0005938 [cell cortex] GO:0015629 [actin cytoskeleton] Show all	980 aa 110 kDa	No	0
RAI14-002 ENSP00000265109 ENST00000265109	Q9P0K7 [Direct mapping] Ankycorbin Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0005938 [cell cortex] GO:0015629 [actin cytoskeleton] Show all	980 aa 110 kDa	No	0
RAI14-003 ENSP00000421424 ENST00000514873	D6R9G6 [Direct mapping] Ankycorbin Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	126 aa 13.6 kDa	No	0
RAI14-005 ENSP00000422942 ENST00000503673	Q9P0K7 [Direct mapping] Ankycorbin Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0005938 [cell cortex] GO:0015629 [actin cytoskeleton] Show all	980 aa 110 kDa	No	0
RAI14-006 ENSP00000427123 ENST00000515799	Q9P0K7 [Direct mapping] Ankycorbin Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0005938 [cell cortex] GO:0015629 [actin cytoskeleton] Show all	983 aa 110.4 kDa	No	0
RAI14-007 ENSP00000422377 ENST00000512629	Q9P0K7 [Direct mapping] Ankycorbin Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0005938 [cell cortex] GO:0015629 [actin cytoskeleton] Show all	951 aa 106.9 kDa	No	0
RAI14-008 ENSP00000423854 ENST00000506376	Q9P0K7 [Direct mapping] Ankycorbin Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0005938 [cell cortex] GO:0015629 [actin cytoskeleton] Show all	972 aa 109.1 kDa	No	0
RAI14-009 ENSP00000426770 ENST00000508315	D6REL2 [Direct mapping] Ankycorbin Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	125 aa 13.5 kDa	No	0
RAI14-010 ENSP00000422112 ENST00000513974	D6R9G6 [Direct mapping] Ankycorbin Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	126 aa 13.6 kDa	No	0
RAI14-011 ENSP00000422515 ENST00000504052	D6RBY4 [Direct mapping] Ankycorbin Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	114 aa 12.4 kDa	No	0
RAI14-014 ENSP00000422114 ENST00000512305	D6R9G4 [Direct mapping] Ankycorbin Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	107 aa 11.7 kDa	No	0
RAI14-015 ENSP00000424502 ENST00000514036	D6RB27 [Direct mapping] Ankycorbin Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	104 aa 11.3 kDa	No	0
RAI14-017 ENSP00000425115 ENST00000512625	D6RE17 [Direct mapping] Ankycorbin Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	150 aa 16.2 kDa	No	0
RAI14-022 ENSP00000424879 ENST00000514527	D6RF74 [Direct mapping] Ankycorbin Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	139 aa 14.9 kDa	No	0

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The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.