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Several cases of testicular cancers along with few cases of skin, renal, urothelial and pancreatic cancers exhibited moderate nuclear immunoreactivity. Remaining malignant tissues were negative.
GENE INFORMATION
Gene name
BARX2
Synonyms
Description
BARX homeobox 2 (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the homeobox transcription factor family. A highly related protein in mouse has been shown to influence cellular processes that control cell adhesion and remodeling of the actin cytoskeleton in myoblast fusion and chondrogenesis. The encoded protein may also play a role in cancer progression. [provided by RefSeq, Jul 2008]