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Gem (nuclear organelle) associated protein 8 (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene is part of the SMN complex, which is necessary for spliceosomal snRNP assembly in the cytoplasm and pre-mRNA splicing in the nucleus. The encoded protein binds to both SMN1 and the GEMIN6/GEMIN7 heterodimer, mediating their interaction. This protein is found in nuclear Gemini of Cajal bodies (gems) and in the cytoplasm. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010]
Q9NWZ8 [Direct mapping] Gem-associated protein 8 A0A024RBX2 [Target identity:100%; Query identity:100%] Family with sequence similarity 51, member A1, isoform CRA_a
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Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Q9NWZ8 [Direct mapping] Gem-associated protein 8 A0A024RBX2 [Target identity:100%; Query identity:100%] Family with sequence similarity 51, member A1, isoform CRA_a
Show all
Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)