Expression of KIAA0556 in cancer - Summary - The Human Protein Atlas

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KIAA0556

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TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	KIAA0556
Gene description	KIAA0556
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Tissue enhanced (fallopian tube)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Ubiquitous cytoplasmic expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Supported based on 2 antibodies. HPA035089 , HPA035090
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PROGNOSTIC SUMMARY
Prognostic marker in head and neck cancer (favourable).
Head and neck cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA035089	HPA035090

GENE INFORMATION
Gene name	KIAA0556
Synonyms
Description	KIAA0556 (HGNC Symbol)
Entrez gene summary
Chromosome	16
Cytoband	p12.1
Chromosome location (bp)	27550133 - 27780369
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000047578 (version 83.38)
Entrez gene	23247
UniProt	O60303 (UniProt - Evidence at protein level)
neXtProt	NX_O60303
Antibodypedia	KIAA0556 antibodies

PROTEIN BROWSER

KIAA0556-001	KIAA0556-009	KIAA0556-011

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
KIAA0556-001 ENSP00000261588 ENST00000261588	O60303 [Direct mapping] Uncharacterized protein KIAA0556 Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005615 [extracellular space] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005886 [plasma membrane] Show all	1618 aa 180.9 kDa	No	0
KIAA0556-009 ENSP00000454884 ENST00000568258	H3BNJ6 [Direct mapping] Uncharacterized protein KIAA0556 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		249 aa 28.5 kDa	No	0
KIAA0556-011 ENSP00000483214 ENST00000618117	A0A087X098 [Direct mapping] Uncharacterized protein KIAA0556 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		110 aa 13 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.