Cell atlas - VPS13D - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

VPS13D

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Nucleoplasm
	Vesicles

Human cell
	Cytosol
	Nucleoplasm
	Vesicles

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	VPS13D
Gene description	Vacuolar protein sorting 13 homolog D (S. cerevisiae)
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nucleoplasm & vesicles. In addition localized to the cytosol.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (approved), Vesicles (approved)
Additional location	In addition localized to the Cytosol (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA027332
	SHOW MORE

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nucleoplasm & vesicles. In addition localized to the cytosol.

Main location

Nucleoplasm (approved), Vesicles (approved)

Additional location

Cytosol (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA027332	A-431	Nucleoplasm
			Vesicles
			Cytosol
	HPA027332	SiHa	Nucleoplasm
			Vesicles
			Cytosol
	HPA027332	U-2 OS	Nucleoplasm
	HPA027332	U-2 OS	Cytosol

GENE INFORMATION
Gene name	VPS13D (HGNC Symbol)
Synonyms	FLJ10619, KIAA0453
Description	Vacuolar protein sorting 13 homolog D (S. cerevisiae) (HGNC Symbol)
Entrez gene summary	This gene encodes a protein belonging to the vacuolar-protein-sorting-13 gene family. In yeast, vacuolar-protein-sorting-13 proteins are involved in trafficking of membrane proteins between the trans-Golgi network and the prevacuolar compartment. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode distinct isoforms. [provided by RefSeq, Jul 2008]
Chromosome	1
Cytoband
Chromosome location (bp)	12230067 - 12512047
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000048707 (version 83.38)
Entrez gene	55187
UniProt	Q5THJ4 (UniProt - Evidence at protein level)
neXtProt	NX_Q5THJ4
Antibodypedia	VPS13D antibodies

PROTEIN BROWSER

VPS13D-001	VPS13D-003	VPS13D-006	VPS13D-014

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
VPS13D-001 ENSP00000478104 ENST00000620676	Q5THJ4 [Direct mapping] Vacuolar protein sorting-associated protein 13D Show all	SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005623 [cell] GO:0006623 [protein targeting to vacuole] GO:0019898 [extrinsic component of membrane] GO:0045053 [protein retention in Golgi apparatus] GO:0070062 [extracellular exosome] Show all	4388 aa 491.9 kDa	No	0
VPS13D-003 ENSP00000482233 ENST00000613099	Q5THJ4 [Direct mapping] Vacuolar protein sorting-associated protein 13D Show all	SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005623 [cell] GO:0006623 [protein targeting to vacuole] GO:0019898 [extrinsic component of membrane] GO:0045053 [protein retention in Golgi apparatus] GO:0070062 [extracellular exosome] Show all	4363 aa 489.1 kDa	No	0
VPS13D-006 ENSP00000441122 ENST00000543766	F5GX56 [Direct mapping] Vacuolar protein sorting-associated protein 13D Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005622 [intracellular] GO:0005623 [cell] GO:0006623 [protein targeting to vacuole] GO:0019898 [extrinsic component of membrane] GO:0045053 [protein retention in Golgi apparatus] Show all	44 aa 5.2 kDa	No	0
VPS13D-014 ENSP00000011700 ENST00000011700	H3BLS7 [Direct mapping] Vacuolar protein sorting-associated protein 13D Show all	SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005623 [cell] GO:0006623 [protein targeting to vacuole] GO:0019898 [extrinsic component of membrane] GO:0045053 [protein retention in Golgi apparatus] Show all	3210 aa 356.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.