Expression of EPN3 in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

EPN3

TISSUE

premium

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	EPN3
Gene description	Epsin 3
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	8
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enhanced (HaCaT, MCF7, RT4, T-47d)
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Mainly cytoplasmic expression in several different tissues types.

ANTIBODY IHC RELIABILITY
Data reliability description	Pending external verification. Caution, Splice and/or transcript discrepancy exists.
Reliability score	Approved based on 1 antibody. HPA055546
	SHOW MORE

PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable).
Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA055546

GENE INFORMATION
Gene name	EPN3 (HGNC Symbol)
Synonyms	FLJ20778, MGC129899
Description	Epsin 3 (HGNC Symbol)
Entrez gene summary
Chromosome	17
Cytoband	q21.33
Chromosome location (bp)	50532543 - 50543750
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000049283 (version 83.38)
Entrez gene	55040
UniProt	Q9H201 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9H201
Antibodypedia	EPN3 antibodies

PROTEIN BROWSER

EPN3-001	EPN3-008	EPN3-009	EPN3-010	EPN3-015	EPN3-017	EPN3-018	EPN3-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
EPN3-001 ENSP00000268933 ENST00000268933	Q9H201 [Direct mapping] Epsin-3 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005905 [coated pit] GO:0008289 [lipid binding] GO:0019897 [extrinsic component of plasma membrane] GO:0030136 [clathrin-coated vesicle] GO:0048471 [perinuclear region of cytoplasm] GO:0070062 [extracellular exosome] GO:1990175 [EH domain binding] Show all	632 aa 68.2 kDa	No	0
EPN3-008 ENSP00000426762 ENST00000503246	D6REL6 [Direct mapping] Epsin-3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		168 aa 19.3 kDa	No	0
EPN3-009 ENSP00000424306 ENST00000503690	D6RBA4 [Direct mapping] Epsin-3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		11 aa 1.3 kDa	No	0
EPN3-010 ENSP00000422682 ENST00000514874	D6RBI9 [Direct mapping] Epsin-3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		51 aa 5.7 kDa	No	0
EPN3-015 ENSP00000426676 ENST00000507709	D6RF39 [Direct mapping] Epsin-3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		17 aa 1.9 kDa	No	0
EPN3-017 ENSP00000422601 ENST00000515126	D6RBR6 [Direct mapping] Epsin-3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		108 aa 12.5 kDa	No	0
EPN3-018 ENSP00000421515 ENST00000507467	D6RFG3 [Direct mapping] Epsin-3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		136 aa 15.7 kDa	No	0
EPN3-201 ENSP00000439512 ENST00000537145	I6L9I8 [Direct mapping] EPN3 protein; Epsin-3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		318 aa 36.2 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.