Expression of FAM160A2 in cancer - Summary - The Human Protein Atlas

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FAM160A2

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	FAM160A2
Gene description	Family with sequence similarity 160, member A2
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

General cytoplasmic expression with a granular pattern.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA055994
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA055994

GENE INFORMATION
Gene name	FAM160A2 (HGNC Symbol)
Synonyms	C11orf56, DKFZP566M1046, FLJ22665, KIAA1759
Description	Family with sequence similarity 160, member A2 (HGNC Symbol)
Entrez gene summary
Chromosome	11
Cytoband	p15.4
Chromosome location (bp)	6211335 - 6234711
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000051009 (version 83.38)
Entrez gene	84067
UniProt	Q8N612 (UniProt - Evidence at protein level)
neXtProt	NX_Q8N612
Antibodypedia	FAM160A2 antibodies

PROTEIN BROWSER

FAM160A2-001	FAM160A2-002	FAM160A2-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FAM160A2-001 ENSP00000265978 ENST00000265978	Q8N612 [Direct mapping] FTS and Hook-interacting protein Show all	SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0007032 [endosome organization] GO:0007040 [lysosome organization] GO:0008333 [endosome to lysosome transport] GO:0015031 [protein transport] GO:0045022 [early endosome to late endosome transport] GO:0070695 [FHF complex] Show all	986 aa 107.1 kDa	No	0
FAM160A2-002 ENSP00000416918 ENST00000449352	Q8N612 [Direct mapping] FTS and Hook-interacting protein Show all	SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0007032 [endosome organization] GO:0007040 [lysosome organization] GO:0008333 [endosome to lysosome transport] GO:0015031 [protein transport] GO:0045022 [early endosome to late endosome transport] GO:0070695 [FHF complex] Show all	972 aa 105.6 kDa	No	0
FAM160A2-003 ENSP00000431773 ENST00000524416	E9PJK5 [Direct mapping] FTS and Hook-interacting protein Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 3TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all		838 aa 91.7 kDa	No	3

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.