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Term
Gene name

Class

Subclass

Chromosome

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In atlas

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Reliability

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Method

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Method

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CBLN4
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PATHOLOGY ATLAS

GENE/PROTEIN

Dictionary

GENERAL INFORMATION

Gene name

CBLN4

Gene description

Cerebellin 4 precursor

Protein class

Plasma proteins
Predicted secreted proteins

Predicted localization

Secreted

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):Mixed
HPA (cell line):Cell line enriched (SH-SY5Y)
HPA (normal tissue):Tissue enhanced (adrenal gland, cerebral cortex, epididymis)

Protein evidence

Evidence at protein level

ANTIBODY IHC RELIABILITY

Reliability score

Pending cancer tissue analysis.

PROGNOSTIC SUMMARY

Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW

TCGA dataset
RNA cancer category: Mixed

PROTEIN EXPRESSION

Pending cancer tissue analysis


STAINING SUMMARY

 

GENE INFORMATION

Gene name

CBLN4 (HGNC Symbol)

Synonyms

CBLNL1, dJ885A10.1

Description

Cerebellin 4 precursor (HGNC Symbol)

Entrez gene summary

This gene encodes a member of a family of small secreted proteins containing C1Q domains. Members of this family are involved in regulation of neurexin signalling during synapse development. The mouse homolog of the protein encoded by this gene competes with netrin to bind to the deleted in colorectal cancer receptor. [provided by RefSeq, Aug 2012]

Chromosome

20

Cytoband

q13.2

Chromosome location (bp)

55997440 - 56005472

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000054803 (version 83.38)

Entrez gene

140689

UniProt

Q9NTU7 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NTU7

Antibodypedia

CBLN4 antibodies

PROTEIN BROWSER

CBLN4-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CBLN4-001
ENSP00000064571
ENST00000064571
Q9NTU7 [Direct mapping]
Cerebellin-4
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   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005615 [extracellular space]
GO:0005623 [cell]
GO:0009306 [protein secretion]
GO:0030054 [cell junction]
GO:0045202 [synapse]
Show all
201 aa
21.8 kDa
Yes 0

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