Expression of GINM1 in cancer - Summary - The Human Protein Atlas

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GINM1

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	GINM1
Gene description	Glycoprotein integral membrane 1
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

General cytoplasmic expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 2 antibodies. HPA017210 , HPA041679
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA017210	HPA041679

GENE INFORMATION
Gene name	GINM1 (HGNC Symbol)
Synonyms	C6orf72, dJ12G14.2
Description	Glycoprotein integral membrane 1 (HGNC Symbol)
Entrez gene summary
Chromosome	6
Cytoband	q25.1
Chromosome location (bp)	149566294 - 149591748
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000055211 (version 83.38)
Entrez gene	116254
UniProt	Q9NU53 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9NU53
Antibodypedia	GINM1 antibodies

PROTEIN BROWSER

GINM1-001	GINM1-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GINM1-001 ENSP00000356389 ENST00000367419	Q9NU53 [Direct mapping] Glycoprotein integral membrane protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] GO:0070062 [extracellular exosome] Show all	330 aa 36.8 kDa	Yes	1
GINM1-002 ENSP00000407343 ENST00000433539	Q5TFA5 [Direct mapping] Glycoprotein integral membrane protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		125 aa 14.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.