Tissue expression of CDK14 - Summary - The Human Protein Atlas

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CDK14

TISSUE

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CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	CDK14
Gene description	Cyclin-dependent kinase 14
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	9
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic and nuclear expression in most tissues.

DATA RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Approved based on 1 antibody. HPA015267
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

N/A

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	CDK14 (HGNC Symbol)
Synonyms	PFTAIRE1, PFTK1
Description	Cyclin-dependent kinase 14 (HGNC Symbol)
Entrez gene summary	PFTK1 is a member of the CDC2 (MIM 116940)-related protein kinase family (Yang and Chen, 2001 [PubMed 11313143]).[supplied by OMIM, Mar 2008]
Chromosome	7
Cytoband	q21.13
Chromosome location (bp)	90466424 - 91210590
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000058091 (version 83.38)
Entrez gene	5218
UniProt	O94921 (UniProt - Evidence at protein level)
neXtProt	NX_O94921
Antibodypedia	CDK14 antibodies

PROTEIN BROWSER

CDK14-001	CDK14-002	CDK14-003	CDK14-007	CDK14-008	CDK14-010	CDK14-011	CDK14-014	CDK14-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CDK14-001 ENSP00000369390 ENST00000380050	O94921 [Direct mapping] Cyclin-dependent kinase 14 Show all	Enzymes ENZYME proteins Transferases Kinases CMGC Ser/Thr protein kinases MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000086 [G2/M transition of mitotic cell cycle] GO:0000308 [cytoplasmic cyclin-dependent protein kinase holoenzyme complex] GO:0004672 [protein kinase activity] GO:0004693 [cyclin-dependent protein serine/threonine kinase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0005886 [plasma membrane] GO:0006468 [protein phosphorylation] GO:0016055 [Wnt signaling pathway] GO:0030332 [cyclin binding] GO:0051301 [cell division] GO:0051726 [regulation of cell cycle] GO:0060828 [regulation of canonical Wnt signaling pathway] Show all	469 aa 53.1 kDa	No	0
CDK14-002 ENSP00000265741 ENST00000265741	O94921 [Direct mapping] Cyclin-dependent kinase 14 Show all	Enzymes ENZYME proteins Transferases Kinases CMGC Ser/Thr protein kinases MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000086 [G2/M transition of mitotic cell cycle] GO:0000308 [cytoplasmic cyclin-dependent protein kinase holoenzyme complex] GO:0004672 [protein kinase activity] GO:0004693 [cyclin-dependent protein serine/threonine kinase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005886 [plasma membrane] GO:0006468 [protein phosphorylation] GO:0016055 [Wnt signaling pathway] GO:0030332 [cyclin binding] GO:0051301 [cell division] GO:0051726 [regulation of cell cycle] GO:0060828 [regulation of canonical Wnt signaling pathway] Show all	451 aa 50.7 kDa	No	0
CDK14-003 ENSP00000385034 ENST00000406263	O94921 [Direct mapping] Cyclin-dependent kinase 14 Show all	Enzymes ENZYME proteins Transferases Kinases CMGC Ser/Thr protein kinases MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000086 [G2/M transition of mitotic cell cycle] GO:0000308 [cytoplasmic cyclin-dependent protein kinase holoenzyme complex] GO:0004672 [protein kinase activity] GO:0004693 [cyclin-dependent protein serine/threonine kinase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0005886 [plasma membrane] GO:0006468 [protein phosphorylation] GO:0016055 [Wnt signaling pathway] GO:0030332 [cyclin binding] GO:0051301 [cell division] GO:0051726 [regulation of cell cycle] GO:0060828 [regulation of canonical Wnt signaling pathway] Show all	423 aa 47.8 kDa	No	0
CDK14-007 ENSP00000393616 ENST00000449528	C9IYJ9 [Direct mapping] Cyclin-dependent kinase 14 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004672 [protein kinase activity] GO:0005524 [ATP binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006468 [protein phosphorylation] Show all	127 aa 14.1 kDa	No	0
CDK14-008 ENSP00000394570 ENST00000430760	C9IYJ9 [Direct mapping] Cyclin-dependent kinase 14 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004672 [protein kinase activity] GO:0005524 [ATP binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006468 [protein phosphorylation] Show all	127 aa 14.1 kDa	No	0
CDK14-010 ENSP00000410770 ENST00000446224	C9IYJ9 [Direct mapping] Cyclin-dependent kinase 14 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004672 [protein kinase activity] GO:0005524 [ATP binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006468 [protein phosphorylation] Show all	127 aa 14.1 kDa	No	0
CDK14-011 ENSP00000406848 ENST00000456689	C9IYJ9 [Direct mapping] Cyclin-dependent kinase 14 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004672 [protein kinase activity] GO:0005524 [ATP binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0006468 [protein phosphorylation] Show all	127 aa 14.1 kDa	No	0
CDK14-014 ENSP00000401603 ENST00000446790	C9JWL6 [Direct mapping] Cyclin-dependent kinase 14 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		92 aa 10.3 kDa	No	0
CDK14-201 ENSP00000398936 ENST00000436577	E7EUK8 [Direct mapping] Cyclin-dependent kinase 14 Show all	MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004672 [protein kinase activity] GO:0005524 [ATP binding] GO:0006468 [protein phosphorylation] Show all	340 aa 38.3 kDa	No	0

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