We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
The protein encoded by this gene belongs to the SECY/SEC61- alpha family. It appears to play a crucial role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum. This protein found to be tightly associated with membrane-bound ribosomes, either directly or through adaptor proteins. This gene encodes an alpha subunit of the heteromeric SEC61 complex, which also contains beta and gamma subunits. [provided by RefSeq, Jul 2008]
P61619 [Direct mapping] Protein transport protein Sec61 subunit alpha isoform 1 B3KNF6 [Target identity:100%; Query identity:100%] Sec61 alpha 1 subunit (S. cerevisiae), isoform CRA_c; cDNA FLJ14517 fis, clone NT2RM1000833, highly similar to Protein transport protein Sec61 subunit alpha isoform 1; cDNA FLJ90225 fis, clone NT2RM1000855, highly similar to Protein transport protein Sec61 subunit alpha isoform 1
Show all
Transporters Primary Active Transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 9TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Show all
GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I] GO:0002479 [antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent] GO:0005515 [protein binding] GO:0005791 [rough endoplasmic reticulum] GO:0005829 [cytosol] GO:0006614 [SRP-dependent cotranslational protein targeting to membrane] GO:0006620 [posttranslational protein targeting to membrane] GO:0007029 [endoplasmic reticulum organization] GO:0015031 [protein transport] GO:0016020 [membrane] GO:0016049 [cell growth] GO:0030176 [integral component of endoplasmic reticulum membrane] GO:0030968 [endoplasmic reticulum unfolded protein response] GO:0034341 [response to interferon-gamma] GO:0036498 [IRE1-mediated unfolded protein response] GO:0042590 [antigen processing and presentation of exogenous peptide antigen via MHC class I] GO:0043022 [ribosome binding] GO:0044267 [cellular protein metabolic process] GO:0045047 [protein targeting to ER]
B4DR61 [Direct mapping] Protein transport protein Sec61 subunit alpha isoform 1; cDNA FLJ59739, highly similar to Protein transport protein Sec61 subunit alpha isoform 1
P61619 [Direct mapping] Protein transport protein Sec61 subunit alpha isoform 1
Show all
Transporters Primary Active Transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014)
Show all
GO:0002474 [antigen processing and presentation of peptide antigen via MHC class I] GO:0002479 [antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent] GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0006614 [SRP-dependent cotranslational protein targeting to membrane] GO:0006620 [posttranslational protein targeting to membrane] GO:0007029 [endoplasmic reticulum organization] GO:0015031 [protein transport] GO:0016020 [membrane] GO:0016049 [cell growth] GO:0030176 [integral component of endoplasmic reticulum membrane] GO:0030968 [endoplasmic reticulum unfolded protein response] GO:0036498 [IRE1-mediated unfolded protein response] GO:0042590 [antigen processing and presentation of exogenous peptide antigen via MHC class I] GO:0043022 [ribosome binding] GO:0044267 [cellular protein metabolic process] GO:0045047 [protein targeting to ER]
