Expression of FLYWCH1 in cancer - Summary - The Human Protein Atlas

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FLYWCH1

TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	FLYWCH1
Gene description	FLYWCH-type zinc finger 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	9
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

General cytoplasmic expression with occasional nuclear expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 2 antibodies. HPA040753 , HPA041001
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA040753	HPA041001

GENE INFORMATION
Gene name	FLYWCH1 (HGNC Symbol)
Synonyms	DKFZp761A132
Description	FLYWCH-type zinc finger 1 (HGNC Symbol)
Entrez gene summary
Chromosome	16
Cytoband	p13.3
Chromosome location (bp)	2911937 - 2951208
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000059122 (version 83.38)
Entrez gene	84256
UniProt	Q4VC44 (UniProt - Evidence at protein level)
neXtProt	NX_Q4VC44
Antibodypedia	FLYWCH1 antibodies

PROTEIN BROWSER

FLYWCH1-001	FLYWCH1-002	FLYWCH1-003	FLYWCH1-006	FLYWCH1-008	FLYWCH1-010	FLYWCH1-011	FLYWCH1-013	FLYWCH1-014

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FLYWCH1-001 ENSP00000253928 ENST00000253928	Q4VC44 [Direct mapping] FLYWCH-type zinc finger-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0046872 [metal ion binding] Show all	716 aa 80.1 kDa	No	0
FLYWCH1-002 ENSP00000399938 ENST00000416288	Q4VC44 [Direct mapping] FLYWCH-type zinc finger-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0046872 [metal ion binding] Show all	715 aa 80 kDa	No	0
FLYWCH1-003 ENSP00000458661 ENST00000573564	I3L188 [Direct mapping] FLYWCH-type zinc finger-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		467 aa 53.1 kDa	No	0
FLYWCH1-006 ENSP00000344122 ENST00000344592	J3KNW1 [Direct mapping] FLYWCH-type zinc finger-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		494 aa 55.8 kDa	No	0
FLYWCH1-008 ENSP00000458282 ENST00000570425	I3L0R3 [Direct mapping] FLYWCH-type zinc finger-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		47 aa 5 kDa	No	0
FLYWCH1-010 ENSP00000459326 ENST00000573525	I3L231 [Direct mapping] FLYWCH-type zinc finger-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		77 aa 8.1 kDa	No	0
FLYWCH1-011 ENSP00000461566 ENST00000571580	I3L4V9 [Direct mapping] FLYWCH-type zinc finger-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		198 aa 21.7 kDa	No	0
FLYWCH1-013 ENSP00000459480 ENST00000575679	I3L287 [Direct mapping] FLYWCH-type zinc finger-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		93 aa 10.4 kDa	No	0
FLYWCH1-014 ENSP00000458689 ENST00000571983	I3L1A7 [Direct mapping] FLYWCH-type zinc finger-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		78 aa 8.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.